Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9191 | 9191-30915 | Brazil | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, L74V, M184V, L210W, T215Y | D67G, K219D | K103N, Y181I | E40F, S68G, V118VI, K122E, D123N, I135T, I142IV, D177E, G196E, T200TI |
| >9191-30915| codons 38-247 CTFLEKEGKISKIGPENPYNTPVFAIKKKGGTKWRKVVDFRELNKRTQDFWEVQLGIPHP AGLKKNKSVTVLDVGDAYFSIPLDENFRKYTAFTIPSTNNETPGVRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPEIVIIQYVDDLYVGSDLEIEQHRIKIEELRQHLWRWGFYTP DDKHQKEPPFLWMGYELHPDKWTVQPIVLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54V, L76V, I84V | L10F, L24I | E34Q, M36V, R41K, K55R, I62V, L63P, I64V |
| >9191-30915| codons 4-99 TLWQRPFVTIKIGGQLKEALIDTGADDTVLQEVNLPGKWKPKIIGGIGGFVRVRQYDQVP VEICGHKAIGTVVVGPTPVNVIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |