<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
48-9189 9189-30908 Brazil 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, K70R, M184I, L210W, T215Y K219Q Y181C A98G, F227L T39AE, E44D, K102KQ, K104KN, T107S, V118I, K122E, I135T, S162A, V179I, G196GE, Q197QK, T200A, I202V, E203K, Q207E, H208Y, R211K, K223E, L228H, V245Q  
>9189-30908| codons 38-247
CEELEKDGKISKIGPENPYNTPVFAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHP
GGLKQKNSVSVLDVGDAYFSIPLDEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP
AIFQASMTKILEPFRKQNPDIIICQYIDDLYVGSDLEIEKHRAKVKELREYLWKWGFYTP
DQKHQEEPPLHWMGYELHPDKWTVQPIQLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46MIL, I54V, V82A, I84V, L90M V11VI, L33F, Q58QE L10I, I13V, I15V, K20R, E35D, M36I, N37DE, K55R, R57K, D60E, I62V, L63P, A71V, I85V, Q92K, I93L  
>9189-30908| codons 4-99
TLWQRPIITVKVGGQLREALLDTGADDTVFEDIELPGRWKPKLIGGIGGFVRVKEYEQVP
IEICGHKVIGTVLVGPTPANVVGRNLMTKLGCTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006