Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9190 | 9190-30908 | Brazil | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, K70KR, L74IV, M184V, T215F | K219Q | K101E, Y181C, G190A | T39TA, K65KE, K122KE, D123E, S162A, D177E, I195IT, V245K |
| >9190-30908| codons 38-247 CAELEKEGKISKIGPENPYNTPVFAIKEKNSTRWRKVVDFRELNKRTQDFWEVQLGIPHP AGLEKKKSVTVLDVGDAYFSVPLDEEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQASMTKILEPFRKQNPEIVICQYVDDLYVASDLETGQHRTKIEELRQHLLRWGFFTP DQKHQKEPPFLWMGYELHPDKWTVQPIKLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, I54V, V82A, I84V | L24I, L33F, K43T, G73GS | L10I, I13IV, K20KR, E35D, M36IL, D60E, I62V, L63P, A71V |
| >9190-30908| codons 4-99 TLWQRPIVTVKIGGQLREALIDTGADDTVFEDLNLPGRWTPKLIGGIGGFVKVRQYEQVP IEICGHKVISTVLVGPTPANVIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |