Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9185 | 9185-30901 | Brazil | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, K70R, L74I, M184V, L210W, T215Y | K219KE | K103N | V108I, K238KN | V60VI, V118VI, K122E, I135T, T139TI, K166R, I202IV, R211K, E224ED, L228LH, V245E | I142LMPT |
| >9185-30901| codons 38-247 CTELEKEGKISKIGPENPYNTPIFAIKKKNSTRWRKIVDFRELNKRTQDFWEVQLGIPHP AGLKKNKSVTILDVGDAYFSIPLDEDFRKYTAFTIPSTNNEIPGTRYQYNVLPQGWKGSP AIFQSSMTRILEPFRKQNPDIVIYQYVDDLYVGSDLEIGQHRTKVEELRQHLWKWGFYTP DEKHQKDPPFHWMGYELHPDNWTVQPIELP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V32I, M46L, V82A | L10I, I13V, I15V, K20R, M36I, K43R, L63P, I64V, A71V |
| >9185-30901| codons 4-99 TLWQRPIVTVKVGGQLREALLDTGADDTILEEINLPGRWRPKLIGGIGGFIKVRQYDQIP VEICGHKVIGTVLVGPTPANIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |