Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9184 | 9184-30901 | Brazil | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, Q151M, M184MV, L210W, T215Y | F116Y | V60I, K101Q, D121Y, K122E, D123E, S162C, I167V, Q174R, D177E, T200A, I202IV, H208Y, R211K, V245T | N137NH |
| >9184-30901| codons 38-247 CTELEKEGKISKIGPENPYNTPIFAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHP AGLQKKKSVTVLDVGDAYYSVPLYEEFRKYTAFTIPSINHETPGIRYQYNVLPMGWKGSP AIFQCSMTKVLEPFRKRNPEIVIYQYVDDLYVGSDLEIGQHRAKVEELRQYLWKWGFYTP DKKHQKEPPFLWMGYELHPDKWTVQPITLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, I54V, V82A, L90M | L33F, K43T, F53L, N83D | L10I, I13V, K20R, M36L, N37T, K55KR, R57RK, D60DE, I62V, L63P, I64V, L89LM |
| >9184-30901| codons 4-99 TLWQRPIVTVKIGGQLREALLDTGADDTVFEELTLPGRWTPKLIGGIGGLVRVKQYEQVP VEICGHKAIGTVLVGPTPADIIGRNMMTQIGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |