<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
48-9345 9345-30923 Brazil 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, T69D, L74V, L210W, T215Y K219KR L100I, K103N   E42EG, K43Q, E44D, K65KE, V111I, V118I, D123E, I135T, D177E, E203EK, Q207E, H208HY, R211K, K223Q  
>9345-30923| codons 38-247
CTELGQDGKISKIGPENPYNTPVFAIKEKNSDKWRKVVDFRELNKRTQDFWEVQLGIPHP
AGIKKNKSVTVLDIGDAYFSIPLDKEFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP
AIFQSSMTKILEPFRKQNPEIVIYQYMDDLYVGSDLEIGQHRTKIKELREYLWKWGFYTP
DRKHQQEPPFLWMGYELHPDKWTVQPIVLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46MI, I50IV, I54V, V82A, I84IV Q58E L10I, I15V, G16GE, L19I, K20R, E35D, M36I, R57K, D60DE, I62V, L63S, I64L, A71V, V77VI, I93IL  
>9345-30923| codons 4-99
TLWQRPIVTIKVEGQIREALLDTGADDTVLEDINLPGRWKPKIIGGVGGFVKVKEYEQVS
LEICGHKVIGTVLIGPTPANVIGRNLLTQLGCTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006