<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
48-9224 9224-30915 Brazil 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, T69D, K70R, L74I, M184V, L210W, T215F V75A, K219Q K103N, Y181C, G190A   K122P, I142V, S162SN, D177E, G196K, I202V, R211K, H221Y, L228H, V245K  
>9224-30915| codons 38-247
CTEMEKEGKISKIGPENPYNTPVFAIKKKNSDRWRKIADFRELNKRTQDFWEVQLGIPHP
AGLKKNKSVTVLDVGDAYFSVPLDPDFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSP
AIFQNSMTKILEPFRKQNPEIVICQYVDDLYVASDLEIKQHRTKVEELRQHLWKWGFFTP
DQKYQKEPPFHWMGYELHPDKWTVQPIKLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I47IV, I54V, V82A, L90M G73GS L10I, K20KR, M36MI, N37D, I62IV, L63P, A71V, I93L  
>9224-30915| codons 4-99
TLWQRPIVTIKIGGQLREALLDTGADDTVLEEIDLPGRWKPKIVGGIGGFVKVRQYDQVP
IEICGHKVISTVLVGPTPANIIGRNLMTQLGCTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006