Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9224 | 9224-30915 | Brazil | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, T69D, K70R, L74I, M184V, L210W, T215F | V75A, K219Q | K103N, Y181C, G190A | K122P, I142V, S162SN, D177E, G196K, I202V, R211K, H221Y, L228H, V245K |
| >9224-30915| codons 38-247 CTEMEKEGKISKIGPENPYNTPVFAIKKKNSDRWRKIADFRELNKRTQDFWEVQLGIPHP AGLKKNKSVTVLDVGDAYFSVPLDPDFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSP AIFQNSMTKILEPFRKQNPEIVICQYVDDLYVASDLEIKQHRTKVEELRQHLWKWGFFTP DQKYQKEPPFHWMGYELHPDKWTVQPIKLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I47IV, I54V, V82A, L90M | G73GS | L10I, K20KR, M36MI, N37D, I62IV, L63P, A71V, I93L |
| >9224-30915| codons 4-99 TLWQRPIVTIKIGGQLREALLDTGADDTVLEEIDLPGRWKPKIVGGIGGFVKVRQYDQVP IEICGHKVISTVLVGPTPANIIGRNLMTQLGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |