Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9268 | 9268-30915 | Brazil | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, V75M, L210W, T215Y | F77L | Y188L, G190GA | K43Q, K49R, V118I, K122E, I135T, T139TI, G141GA, V179VI, V189I, R211K, L228H, V245E |
| >9268-30915| codons 38-247 CTELEQEGKISRIGPENPYNTPVFAIKKKDSTKWRKLMDLRELNKRTQDFWEVQLGIPHP AGLKKKKSVTVLDVGDAYFSIPLDEDFRKYTAFTIPSTNNEIPAIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPDIIIYQYMDDLLIASDLEIGQHRTKIEELRQHLWKWGFYTP DKKHQKEPPFHWMGYELHPDKWTVQPIELP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54V, V82A | L24I, G73C | L10I, I15V, E35D, M36I, K55R, D60E, I62V, L63P, I72L |
| >9268-30915| codons 4-99 TLWQRPIVTIKVGGQLKEALIDTGADDTVLEDINLPGRWKPKIIGGIGGFVRVRQYEQVP IEICGHKALCTVLVGPTPANIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |