<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
48-9215 9215-30908 Brazil 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, T69D, L74V, L210W, T215Y   K103S, Y181C, G190A   T39A, K101Q, V118I, K122E, I135T, S162SN, V179I, G196E, T200A, E203V, Q207E E138M
>9215-30908| codons 38-247
CAELEKEGKISKIGPENPYNTPVFAIKKKNSDKWRKVVDFRELNKRTQDFWEVQLGIPHP
AGLQKSKSVTVLDVGDAYFSIPLDEDFRKYTAFTIPSTNNMTPGIRYQYNVLPQGWKGSP
AIFQNSMTKILEPFRKQNPDIIICQYMDDLYVASDLEIEQHRAKIVELREHLWRWGFYTP
DKKHQKEPPFLWMGYELHPDKWTVQPIVLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54M, L76V, L90M L10F, Q58E I13V, K20I, E35K, N37D, L38W, R41K, F53Y, K55R, R57K, I62V, L63P, I64V, A71V, I72IM, L89LM, I93IL M36F
>9215-30908| codons 4-99
TLWQRPFVTVKIGGQLIEALLDTGADDTVLEKFDWPGKWKPKIIGGIGGYMRVKEYDQVP
VEICGHKVMGTVVVGPTPVNIIGRNMMTQLGCTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006