Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9215 | 9215-30908 | Brazil | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54M, L76V, L90M | L10F, Q58E | I13V, K20I, E35K, N37D, L38W, R41K, F53Y, K55R, R57K, I62V, L63P, I64V, A71V, I72IM, L89LM, I93IL | M36F |
| >9215-30908| codons 4-99 TLWQRPFVTVKIGGQLIEALLDTGADDTVLEKFDWPGKWKPKIIGGIGGYMRVKEYDQVP VEICGHKVMGTVVVGPTPVNIIGRNMMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, T69D, L74V, L210W, T215Y | K103S, Y181C, G190A | T39A, K101Q, V118I, K122E, I135T, S162SN, V179I, G196E, T200A, E203V, Q207E | E138M |
| >9215-30908| codons 38-247 CAELEKEGKISKIGPENPYNTPVFAIKKKNSDKWRKVVDFRELNKRTQDFWEVQLGIPHP AGLQKSKSVTVLDVGDAYFSIPLDEDFRKYTAFTIPSTNNMTPGIRYQYNVLPQGWKGSP AIFQNSMTKILEPFRKQNPDIIICQYMDDLYVASDLEIEQHRAKIVELREHLWRWGFYTP DKKHQKEPPFLWMGYELHPDKWTVQPIVLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |