Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9216 | 9216-30908 | Brazil | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V82A, I84IV, L90M | Q58E | L10I, T12TA, L19LV, D60E, I62V, L63P, A71AT, V77I, I93L |
| >9216-30908| codons 4-99 TLWQRPIVAIKIGGQVKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVREYEQVP IEICGHKTIGTVLIGPTPANVIGRNLMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67DN, T69TADN, M184MV, T215Y | Y181YC | V118VI, K122E, D123N, I135T, I142IV, D177E, I178M, T200A, R211K, V245T |
| >9216-30908| codons 38-247 CTELEKEGKISKIGPENPYNTPVFAIKKKNSNKWRKLVDFRELNKRTQDFWEVQLGIPHP AGLKKKKSVTVLDVGDAYFSIPLDENFRKYTAFTIPSTNNETPGVRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPEMVICQYVDDLYVGSDLEIGQHRAKIEELRQHLLKWGFYTP DKKHQKEPPFLWMGYELHPDKWTVQPITLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |