Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9039 | 9039-30901 | Brazil | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I47V, I54M, I84V, L90M | L10F, V11IL, G73S, L89V | K20I, E34Q, E35ED, M36MI, N37S, L63P, H69K, A71V, I85V, I93L |
| >9039-30901| codons 4-99 TLWQRPFLTIKIGGQLIEALLDTGADDTVLQDISLPGRWKPKIVGGIGGFMKVRQYDQIP IEICGKKVISTVLVGPTPVNVVGRNVMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, M184V, L210W, T215Y | V75L, F77L | K103N | V118I, K122E, I135T, D177DN, Q197E, T200K, R211H |
| >9039-30901| codons 38-247 CTELEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLLDLRELNKRTQDFWEVQLGIPHP AGLKKNKSVTVLDVGDAYFSIPLDEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPNIVIYQYVDDLYVGSDLEIGEHRKKIEELRQHLWHWGFYTP DKKHQKEPPFLWMGYELHPDKWTVQPIVLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |