Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9038 | 9038-30901 | Brazil | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, I54V, V82A, L90M | L33F, G73S | L10I, G16A, L24F, K55R, R57K, D60E, I62V, L63P, A71V, I72L |
| >9038-30901| codons 4-99 TLWQRPIVTIKIAGQLKEALFDTGADDTVFEEMNLPGRWKPKLIGGIGGFVRVKQYEQVP IEICGHKVLSTVLVGPTPANIIGRNLMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, T215F | K219Q | K103S, G190A | K101Q, K122E, I135IV, S162C, I178M, D192N, T200A, E203ED, Q207E, L228H, V245E |
| >9038-30901| codons 38-247 CTEMEKEGKISKIGPENPYNTPVFAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHP AGLQKSKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSP AIFQCSMTKILEPFRKQNPDMVIYQYMDDLYVASNLEIGQHRAKIDELREHLLRWGFFTP DQKHQKEPPFHWMGYELHPDKWTVQPIELP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |