<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
48-9040 9040-30901 Brazil 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, K70R, M184V, L210W, T215Y V75M, K219E G190A   V60I, V118I, K122E, D123E, I135T, S162A, K166Q, D177E, E203K, R211K, D218E, V245KM  
>9040-30901| codons 38-247
CTELEKEGKISKIGPENPYNTPIFAIKKKNSTRWRKLMDFRELNKRTQDFWEVQLGIPHP
AGLKKKKSVTVLDVGDAYFSIPLDEEFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP
AIFQASMTQILEPFRKQNPEIVIYQYVDDLYVASDLEIGQHRTKIKELRQHLWKWGFYTP
EEKHQKEPPFLWMGYELHPDKWTVQPIMLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I54V, L76V, I84V, L90M L10F, V11VI, L89LV I13V, Q18H, K20I, E34EK, M36I, I62V, L63P, A71V  
>9040-30901| codons 4-99
TLWQRPFITVKIGGHLIEALLDTGADDTVLKEINLPGRWKPKMIGGIGGFVKVRQYDQVP
IEICGHKVIGTVVVGPTPVNVIGRNVMTQIGCTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006