<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
48-9026 9026-30825 Brazil 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, L74V, M184V, L210W, T215Y K219N K101E, Y181C, G190S   V90I, V118I, K122E, D123N, I135T, Q174K, D177E, T200A, I202V, R211K, V245M  
>9026-30825| codons 38-247
CTELEKEGKISKIGPENPYNTPVFAIKKKNSTKWRKVVDFRELNKRTQDFWEIQLGIPHP
AGLEKKKSVTVLDVGDAYFSIPLDENFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP
AIFQSSMTKILEPFRKKNPEIVICQYVDDLYVSSDLEIGQHRAKVEELRQHLWKWGFYTP
DNKHQKEPPFLWMGYELHPDKWTVQPIMLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46ML, V82A, L90M Q58QE L10I, I15V, G17GD, K20MR, E35ED, M36I, N37ND, I62V, L63P, A71AITV, T74TS, I93L  
>9026-30825| codons 4-99
TLWQRPIVTIKVGDQLREALLDTGADDTVLEDIDLPGRWKPKLIGGIGGFIKVREYDQVP
IEICGHKVIGSVLVGPTPANIIGRNLMTQLGCTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006