Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9026 | 9026-30825 | Brazil | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, L74V, M184V, L210W, T215Y | K219N | K101E, Y181C, G190S | V90I, V118I, K122E, D123N, I135T, Q174K, D177E, T200A, I202V, R211K, V245M |
| >9026-30825| codons 38-247 CTELEKEGKISKIGPENPYNTPVFAIKKKNSTKWRKVVDFRELNKRTQDFWEIQLGIPHP AGLEKKKSVTVLDVGDAYFSIPLDENFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKKNPEIVICQYVDDLYVSSDLEIGQHRAKVEELRQHLWKWGFYTP DNKHQKEPPFLWMGYELHPDKWTVQPIMLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46ML, V82A, L90M | Q58QE | L10I, I15V, G17GD, K20MR, E35ED, M36I, N37ND, I62V, L63P, A71AITV, T74TS, I93L |
| >9026-30825| codons 4-99 TLWQRPIVTIKVGDQLREALLDTGADDTVLEDIDLPGRWKPKLIGGIGGFIKVREYDQVP IEICGHKVIGSVLVGPTPANIIGRNLMTQLGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |