Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9025 | 9025-30825 | Brazil | 2003 | HIV1 | F | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, K70R, L74V, T215Y | K219E | L100I, K103N | T39K, K43E, E44A, K49R, D123E, S162C, E169D, P170PS, K173A, Q174K, D177DN, I178L, Q207A, H208Y, R211K, W212WL, D218E, L228H, V245Q |
| >9025-30825| codons 38-247 CKELEEAGKISRIGPENPYNTPVFAIKKKNSTRWRKVVDFRELNKRTQDFWEVQLGIPHP AGIKKNKSVTVLDVGDAYFSVPLDKEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQCSMTKILDSFRAKNPNLVIYQYMDDLYVGSDLEIGQHRTKIEELRAYLLKLGFYTP EEKHQKEPPFHWMGYELHPDKWTVQPIQLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54S, V82A | L33F | L10I, I13V, I15V, K20M, E35N, M36I, N37D, R41K, K55R, R57K, Q61N, T74S, L89I |
| >9025-30825| codons 4-99 TLWQRPIVTVKVGGQLMEALLDTGADDTVFENIDLPGKWKPKIIGGIGGFSRVKQYDNIL IEICGHKAIGSVLVGPTPANIIGRNILTQIGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |