Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9036 | 9036-30825 | Brazil | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, V75M, L210W, T215Y | K219N | Y181V, G190A | A98G, F227L | K43Q, E44D, K49R, V60I, V106VI, V111I, K122E, D123DE, I135IV, S162D, S163T, M164I, I167V, E169D, I178F, V179I, T200A, E203K, H208Y, R211K, K223E |
| >9036-30825| codons 38-247 CTELEQDGKISRIGPENPYNTPIFAIKKKNSTKWRKLMDFRELNKRTQDFWEVQLGIPHP GGLKKKKSITVLDIGDAYFSVPLDEEFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSP AIFQDTITKVLDPFRKQNPDFIIVQYMDDLYVASDLEIGQHRAKIKELRQYLWKWGFYTP DNKHQEEPPLLWMGYELHPDKWTVQPIVLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54V, I84V, L90M | L10F, G73S | V11L, T12P, I15V, G17E, Q18H, K20I, M36MI, L63P, A71V, I72L, I85V, I93L |
| >9036-30825| codons 4-99 TLWQRPFLPIKVGEHLIEALLDTGADDTVLEEINLPGRWKPKIIGGIGGFVKVRQYDQIP IEICGHKVLSTVLVGPTPVNVVGRNLMTQLGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |