Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9030 | 9030-30825 | Brazil | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, Y115F, Q151M, M184V, T215F | V75I, F77L, F116NY, K219Q | K101E, Y181C, G190A | V108I | V106VI, V118I, I135T, Q174E, E203D, R211K, F214L, L228H, V245T |
| >9030-30825| codons 38-247 CTEMEKEGKISKIGPENPYNTPVFAIKKKNSTKWRKLIDLRELNKRTQDFWEVQLGIPHP AGLEKKKSITILDVGDAFYSIPLDKDFRKYTAFTIPSTNNETPGIRYQYNVLPMGWKGSP AIFQSSMTKILEPFRKENPDIVICQYVDDLYVASDLEIGQHRTKIDELRQHLLKWGLFTP DQKHQKEPPFHWMGYELHPDKWTVQPITLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V32I, M46I, I47V, I54L, I84V | L24I, L33F, K43KT | L10I, I13IV, I15V, L19Q, K20R, E35D, M36I, N37E, R41K, K55N, R57K, I62V, I64V, E65D, A71V, Q92K |
| >9030-30825| codons 4-99 TLWQRPIVTVKVGGQQREALIDTGADDTIFEDIELPGKWTPKIVGGIGGFLNVKQYDQVL VDICGHKVIGTVLVGPTPVNVIGRNLLTKIGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |