Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9027 | 9027-30825 | Brazil | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V32I, I47V, I54M, V82A, L90M | L89V | L10S, I15V, G16A, K20R, E35D, M36I, N37D, R57K, L63P, A71V, I93L | G73E |
| >9027-30825| codons 4-99 TLWQRPSVTIKVAGQLREALLDTGADDTILEDIDLPGRWKPKMVGGIGGFMKVKQYDQIP IEICGHKVIETVLVGPTPANIIGRNVMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, M184V, T215F | K219E | Y181V, G190S | T69H, K102Q, K122E, D123E, I135T, S162C, V245K |
| >9027-30825| codons 38-247 CTEMEKEGKISKIGPENPYNTPVFAIKKKNSHRWRKLVDFRELNKRTQDFWEVQLGIPHP AGLKQKKSVTVLDVGDAYFSVPLDEEFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP AIFQCSMTKILEPFRKQNPDIVIVQYVDDLYVSSDLEIGQHRTKIEELRQHLLRWGFFTP DEKHQKEPPFLWMGYELHPDKWTVQPIKLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |