Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9033 | 9033-30825 | Brazil | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, V75M, L210W, T215Y | V106A, G190A | F227L | T39A, K43E, E44D, K49R, V60I, V118I, K122E, T139K, S162C, I178M, T200A, E203D, H208Y, R211K, W212M, K223Q |
| >9033-30825| codons 38-247 CAELEEDGKISRIGPENPYNTPIFAIKKKNSTKWRKLMDFRELNKRTQDFWEVQLGIPHP AGLKKKKSATVLDVGDAYFSIPLDEDFRKYTAFTIPSINNEKPGIRYQYNVLPQGWKGSP AIFQCSMTKILEPFRKQNPDMVIYQYMDDLYVASDLEIGQHRAKIDELRQYLWKMGFYTP DKKHQQEPPLLWMGYELHPDKWTVQPIVLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54M, I84V, L90M | V11I, G73IT | L10I, T12A, K14R, I15V, Q18H, K20I, M36I, R41K, I62V, L63P, I64V, C67CF, I72L, I85V |
| >9033-30825| codons 4-99 TLWQRPIIAIRVGGHLIEALLDTGADDTVLEEINLPGKWKPKIIGGIGGFMKVRQYDQVP VEIFGHKALTTVLVGPTPVNVVGRNLMTQIGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |