<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
48-9033 9033-30825 Brazil 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, L210W, T215Y V75M V106A, G190A F227L T39A, K43E, E44D, K49R, V60I, V118I, K122E, T139K, S162C, I178M, T200A, E203D, H208Y, R211K, W212M, K223Q  
>9033-30825| codons 38-247
CAELEEDGKISRIGPENPYNTPIFAIKKKNSTKWRKLMDFRELNKRTQDFWEVQLGIPHP
AGLKKKKSATVLDVGDAYFSIPLDEDFRKYTAFTIPSINNEKPGIRYQYNVLPQGWKGSP
AIFQCSMTKILEPFRKQNPDMVIYQYMDDLYVASDLEIGQHRAKIDELRQYLWKMGFYTP
DKKHQQEPPLLWMGYELHPDKWTVQPIVLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54M, I84V, L90M V11I, G73IT L10I, T12A, K14R, I15V, Q18H, K20I, M36I, R41K, I62V, L63P, I64V, C67CF, I72L, I85V  
>9033-30825| codons 4-99
TLWQRPIIAIRVGGHLIEALLDTGADDTVLEEINLPGKWKPKIIGGIGGFMKVRQYDQVP
VEIFGHKALTTVLVGPTPVNVVGRNLMTQIGCTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006