Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9212 | 9212-30929 | Brazil | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, Q151M, T215HY | A62V, V75I, F77L, F116Y, K219E | Y181C, G190A | T69N, K101Q, V179I, I202IV, E203Q, Q207E, L228H |
| >9212-30929| codons 38-247 CTEMEKEGKISKIGPENPYNTPVFVIKKKNSNKWRKLIDLRELNKRTQDFWEVQLGIPHP AGLQKKKSVTVLDVGDAYYSVPLDKDFRKYTAFTIPSINNETPGIRYQYNVLPMGWKGSP AIFQSSMTKILEPFRKQNPDIIICQYMDDLYVASDLEIGQHRTKVQELREHLLRWGFYTP DEKHQKEPPFHWMGYELHPDKWTVQPIVLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54V, L76V, V82F, L90M | L33I, Q58E | L10I, E35D, M36I, N37D, I62V, L63V, I64V, A71V, I93L |
| >9212-30929| codons 4-99 TLWQRPIVTIKIGGQLKEALLDTGADDTVIEDIDLPGRWKPKIIGGIGGFVKVREYDQVV VEICGHKVIGTVVVGPTPFNIIGRNLMTQLGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |