Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9072 | 9072-30901 | Brazil | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, L74V, L210W, T215Y | K219KR | L100I, K103N | K43N, E44D, A98AS, K102R, V118I, K122E, I135T, S162SDGN, K166R, I178IM, G196E, E203K, H208Y, R211K, K223Q, V245M |
| >9072-30901| codons 38-247 CTELENDGKISKIGPENPYNTPVFAIKKKNSTKWRKVVDFRELNKRTQDFWEVQLGIPHP SGIKRNKSVTVLDVGDAYFSIPLDEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP AIFQNSMTRILEPFRKQNPDMVIYQYMDDLYVGSDLEIEQHRTKIKELRQYLWKWGFYTP DRKHQQEPPFLWMGYELHPDKWTVQPIMLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54V, I84V, L90M | L10F, V11I, Q58E, G73S | I13V, I15V, G16A, Q18H, K20I, E35D, M36I, D60E, L63P, A71V, I72L, N83NS, T91S |
| >9072-30901| codons 4-99 TLWQRPFITVKVAGHLIEALLDTGADDTVLEDINLPGRWKPKIIGGIGGFVKVREYEQIP IEICGHKVLSTVLVGPTPVSVIGRNLMSQIGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |