Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9065 | 9065-30825 | Brazil | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, M184V, L210W, T215Y | Y181CFGV | E44D, K49R, K122E, V148VG, V179I, Q207E, R211K, D218E, K223KQ, L228R, V245M |
| >9065-30825| codons 38-247 CTELEKDGKISRIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHP AGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNGLPQGWKGSP AIFQSSMTKILEPFRKQNPDIIIVQYVDDLYVGSDLEIGQHRTKIEELREHLWKWGFYTP EKKHQQEPPFRWMGYELHPDKWTVQPIMLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54V, I84V, L90M | L10F, G73T | L24LS, L63P, I64V, A71V, I72L, V77VI, I85V |
| >9065-30825| codons 4-99 TLWQRPFVTIKIGGQLKEALSDTGADDTVLEEMNLPGRWKPKMIGGIGGFVKVRQYDQIP VEICGHKVLTTVLIGPTPVNVVGRNLMTQIGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |