Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9066 | 9066-30825 | Brazil | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, L210W, T215Y | A62V | K103NS | K238T | K43E, E44A, I94L, V118I, K122E, D123S, I135T, E203K, Q207DE, H208Y, R211K, K223Q, L228R | N54I |
| >9066-30825| codons 38-247 CTELEEAGKISKIGPEIPYNTPVFVIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGLPHP AGLKKSKSVTVLDVGDAYFSIPLDESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIKELREYLWKWGFYTP DKKHQQEPPFRWMGYELHPDTWTVQPIVLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54V, L76V, I84V, L90M | L10F | I13V, I15V, Q18H, K20I, E34K, E35D, M36I, N37D, D60E, L63P, A71V |
| >9066-30825| codons 4-99 TLWQRPFVTVKVGGHLIEALLDTGADDTVLKDIDLPGRWKPKMIGGIGGFVKVRQYEQIP IEICGHKVIGTVVVGPTPVNVIGRNLMTQIGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |