Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9067 | 9067-30825 | Brazil | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V32I, I47V, I54L, I84V, L90M | L33F, G73S | L10I, I13IV, I15V, R57K, L63P, A71V, I72V, Q92QH |
| >9067-30825| codons 4-99 TLWQRPIVTVKVGGQLKEALLDTGADDTIFEEMNLPGRWKPKMVGGIGGFLKVKQYDQIP IEICGHKVVSTVLVGPTPVNVIGRNLMTHIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, T215F | A62V, K219Q | A98AG | T69Y, K122E, I135T, I202V, R211K | I159IR |
| >9067-30825| codons 38-247 CTEMEKEGKISKIGPENPYNTPVFVIKKKNSYRWRKLVDFRELNKRTQDFWEVQLGIPHP GGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP ARFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIGQHRTKVEELRQHLLKWGFFTP DQKHQKEPPFLWMGYELHPDKWTVQPIVLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |