Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9062 | 9062-30820 | Brazil | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, L210W, T215Y | V75VL | G190S | K238N | I135T, K166R, T200A, L228N, V245T |
| >9062-30820| codons 38-247 CTELEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLLDFRELNKRTQDFWEVQLGIPHP AGLKKKKSVTVLDVGDAYFSVPLDKDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP AIFQSSMTRILEPFRKQNPDIVIYQYMDDLYVSSDLEIGQHRAKIEELRQHLWRWGFYTP DKKHQKEPPFNWMGYELHPDNWTVQPITLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I47IV, I54IL, L76V, I84V | L10V, I13V, I15V, G17E, Q18H, K20L, E35D, M36I, F53Y, D60DE, I62V, L63P, A71T, I72T, L89I, I93L |
| >9062-30820| codons 4-99 TLWQRPVVTVKVGEHLLEALLDTGADDTVLEDINLPGRWKPKIVGGIGGYLKVRQYEQVP IEICGHKTTGTVVVGPTPVNVIGRNILTQLGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |