Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9061 | 9061-30820 | Brazil | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54V, V82C, I84V | L10F, L24I, L33F | L63P, A71I, I72T, P79N, T91S, I93L |
| >9061-30820| codons 4-99 TLWQRPFVTIKIGGQLKEALIDTGADDTVFEEMNLPGRWKPKIIGGIGGFVKVRQYDQIP IEICGHKITGTVLVGNTPCNVIGRNLLSQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, M184V, L210W, T215Y | K219Q | E40F, K43E, V111I, K122E, I135T, E138A, S162A, K173N, H208Y, R211K |
| >9061-30820| codons 38-247 CTFLEEEGKISKIGPENPYNTPVFAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHP AGLKKKKSVTVLDIGDAYFSVPLDEDFRKYTAFTIPSTNNATPGIRYQYNVLPQGWKGSP AIFQASMTKILEPFRNQNPDIVIYQYVDDLYVGSDLEIGQHRTKIEELRQYLWKWGFYTP DQKHQKEPPFLWMGYELHPDKWTVQPIVLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |