<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
48-9507 9507-30930 Argentina 2003 HIV1 U Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, L74V, L210W, T215Y K219EG K101E, Y181C, G190A V108VI T39A, K64R, V118I, K122E, F171Y, Q174QKR, D177E, E203K, Q207D, R211KT, D218E  
>9507-30930| codons 38-247
CAELEKEGKISKIGPENPYNTPVFAIRKKNSTKWRKVVDFRELNKRTQDFWEVQLGIPHP
AGLEKKKSVTILDVGDAYFSIPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP
AIFQSSMTKILEPYRKRNPEIVICQYMDDLYVASDLEIGQHRTKIKELRDHLWTWGFYTP
EGKHQKEPPFLWMGYELHPDKWTVQPIVLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I54IV, L90M L10F, G73S K20I, E35D, M36V, R57RK, I62V, L63P, A71T, I72IMR  
>9507-30930| codons 4-99
TLWQRPFVTIKIGGQLIEALLDTGADDTVLEDVNLPGRWKPKMIGGIGGFVKVKQYDQVP
IEICGHKTRSTVLVGPTPVNIIGRNLMTQIGCTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006