Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9507 | 9507-30930 | Argentina | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54IV, L90M | L10F, G73S | K20I, E35D, M36V, R57RK, I62V, L63P, A71T, I72IMR |
| >9507-30930| codons 4-99 TLWQRPFVTIKIGGQLIEALLDTGADDTVLEDVNLPGRWKPKMIGGIGGFVKVKQYDQVP IEICGHKTRSTVLVGPTPVNIIGRNLMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, L74V, L210W, T215Y | K219EG | K101E, Y181C, G190A | V108VI | T39A, K64R, V118I, K122E, F171Y, Q174QKR, D177E, E203K, Q207D, R211KT, D218E |
| >9507-30930| codons 38-247 CAELEKEGKISKIGPENPYNTPVFAIRKKNSTKWRKVVDFRELNKRTQDFWEVQLGIPHP AGLEKKKSVTILDVGDAYFSIPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPYRKRNPEIVICQYMDDLYVASDLEIGQHRTKIKELRDHLWTWGFYTP EGKHQKEPPFLWMGYELHPDKWTVQPIVLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |