Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9506 | 9506-30930 | Argentina | 2003 | HIV1 | F | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54V, V82A, L90M | G73GS | L10I, I15V, K20R, E35D, M36I, N37D, R41K, R57K, Q61N, I62V, L63P, C67F, H69HR |
| >9506-30930| codons 4-99 TLWQRPIVTIKVGGQLREALLDTGADDTVLEDIDLPGKWKPKMIGGIGGFVKVKQYDNVP IEIFGRKAISTVLVGPTPANIIGRNLMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L | K70KT, T215C | K103N, Y188C | T39A, E44ED, S68G, K102R, K122E, D123DN, I135V, V179VI, T200TA, I202V, E224ED, L228H, V245T | L210D |
| >9506-30930| codons 38-247 CAELEKDGKISKIGPENPYNTPVFAIKKKDGTTWRKLVDFRELNKRTQDFWEVQLGIPHP AGLKRNKSVTVLDVGDAYFSVPLDENFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPDIIIYQYMDDLCVGSDLEIGQHRAKVEELRQHLDRWGFCTP DKKHQKDPPFHWMGYELHPDKWTVQPITLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |