Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9373 | 9373-30929 | Brazil | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, T69D, L210W, T215Y | V75S | K101E, Y181I, G190S | K43E, E44A, A98S, V118I, D123E, E169ED, P170PT, D177E, T200A, E203K, H208Y, R211K, K223Q, K238KR, V245VA |
| >9373-30929| codons 38-247 CTELEEAGKISKIGPENPYNTPVFAIKKKNSDKWRKLSDFRELNKRTQDFWEVQLGIPHP SGLEKKKSVTVLDVGDAYFSIPLDKEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILDTFRKQNPEIVIIQYMDDLYVSSDLEIGQHRAKIKELRQYLWKWGFYTP DKKHQQEPPFLWMGYELHPDRWTVQPIALP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, I54V, V82A | L24I, L33F, K43T | L10I, I13V, M36L, N37S, F53I, D60E, I62V, L63P, Q92K |
| >9373-30929| codons 4-99 TLWQRPIVTVKIGGQLKEALIDTGADDTVFEELSLPGRWTPKLIGGIGGIVKVRQYEQVP IEICGHKAIGTVLVGPTPANIIGRNLLTKIGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |