<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
48-9373 9373-30929 Brazil 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46L, I54V, V82A L24I, L33F, K43T L10I, I13V, M36L, N37S, F53I, D60E, I62V, L63P, Q92K  
>9373-30929| codons 4-99
TLWQRPIVTVKIGGQLKEALIDTGADDTVFEELSLPGRWTPKLIGGIGGIVKVRQYEQVP
IEICGHKAIGTVLVGPTPANIIGRNLLTKIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, T69D, L210W, T215Y V75S K101E, Y181I, G190S   K43E, E44A, A98S, V118I, D123E, E169ED, P170PT, D177E, T200A, E203K, H208Y, R211K, K223Q, K238KR, V245VA  
>9373-30929| codons 38-247
CTELEEAGKISKIGPENPYNTPVFAIKKKNSDKWRKLSDFRELNKRTQDFWEVQLGIPHP
SGLEKKKSVTVLDVGDAYFSIPLDKEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP
AIFQSSMTKILDTFRKQNPEIVIIQYMDDLYVSSDLEIGQHRAKIKELRQYLWKWGFYTP
DKKHQQEPPFLWMGYELHPDRWTVQPIALP

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006