Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9338 | 9338-30924 | Brazil | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54V, V82T, I84V, L90M | L33F | L10V, T12S, I13V, L19I, K20R, M36I, N37D, R41K, I62V, L63P, I66F, A71V, T74S |
| >9338-30924| codons 4-99 TLWQRPVVSVKIGGQIREALLDTGADDTVFEEIDLPGKWKPKMIGGIGGFVKVRQYDQVP IEFCGHKVIGSVLVGPTPTNVIGRNLMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, K70R, L210W, T215Y | K219E | E44D, V60I, K104KR, V118I, D121H, K122E, I135T, S162D, K166R, D177E, I178IM, T200A, I202V, H208HY, R211K, L228H |
| >9338-30924| codons 38-247 CTELEKDGKISKIGPENPYNTPIFAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHP AGLKKKRSVTVLDVGDAYFSIPLHEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP AIFQDSMTRILEPFRKQNPEMVIYQYMDDLYVGSDLEIGQHRAKVEELRQYLWKWGFYTP DEKHQKEPPFHWMGYELHPDKWTVQPIVLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |