Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9337 | 9337-30922 | Brazil | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54V, L76V, V82A | L10I, K14R, I15V, N37E, K43R, R57K, I62V, L63P, A71V, I93L |
| >9337-30922| codons 4-99 TLWQRPIVTIRVGGQLKEALLDTGADDTVLEEMELPGRWRPKIIGGIGGFVKVKQYDQVP IEICGHKVIGTVVVGPTPANIIGRNLLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, V75M, M184V, L210W, T215Y | K103NS | K101Q, V118VI, D121H, K122E, I135K, K166R, D177E, I202IV, H221Y, V245M |
| >9337-30922| codons 38-247 CTELEKEGKISKIGPENPYNTPVFAIKKKNSTKWRKLMDFRELNKRTQDFWEVQLGIPHP AGLQKSKSVTVLDVGDAYFSIPLHEDFRKYTAFTIPSKNNETPGIRYQYNVLPQGWKGSP AIFQSSMTRILEPFRKQNPEIVIYQYVDDLYVGSDLEIGQHRTKVEELRQHLWRWGFYTP DKKYQKEPPFLWMGYELHPDKWTVQPIMLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |