Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9192 | 9192-30915 | Brazil | 2003 | HIV1 | F | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| K20R, E35D, M36I, R41K, R57K, Q61N, H69Y, I72T |
| >9192-30915| codons 4-99 TLWQRPLVTIKIGGQLREALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYDNIL IEICGYKATGTVLVGPTPVNIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, M184V | A62V, V75I, K219Q | L109LP, K122E, I135V, S162C, E169ED, K173A, Q174K, I178IL, Q197E, T200TA, Q207E, R211K, D218E, V245Q | L193LS |
| >9192-30915| codons 38-247 CTELEKEGKISKIGPENPYNTPVFVIKKKNSTKWRKLIDFRELNKRTQDFWEVQLGIPHP AGLKKKKSVTVPDVGDAYFSVPLDEDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSP AIFQCSMTKILDPFRAKNPDLVIYQYVDDLYVGSDSEIGEHRAKIEELREHLLKWGFTTP EQKHQKEPPFLWMGYELHPDKWTVQPIQLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |