<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
48-9349 9349-30923 Brazil 2003 HIV1 F Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, T69D, K70R, T215F V75M, K219W K103KN, Y188L   T39A, K43KE, V60I, K101KI, V106L, L109V, K122E, D123N, I135V, E169D, R172RK, K173A, Q174K, T200A, E203D, Q207A, R211T, D218E, L228H  
>9349-30923| codons 38-247
CAELEEEGKISKIGPENPYNTPIFAIKKKNSDRWRKLMDFRELNKRTQDFWEVQLGIPHP
AGLIKNKSLTVVDVGDAYFSVPLDENFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSP
AIFQSSMTKILDPFKAKNPDIVIYQYMDDLLVGSDLEIGQHRAKIDELRAHLLTWGFFTP
EWKHQKEPPFHWMGYELHPDKWTVQPIVLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
V32I, M46I, I47V, G48M, I54M, V82A L33F, F53L L10I, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, I72T, T74S, L89I  
>9349-30923| codons 4-99
TLWQRPIVTIKVGGQLREALLDTGADDTIFEDINLPGKWKPKIVMGIGGLMKVKQYDNIL
IEICGHKATGSVLVGPTPANIIGRNILTQIGCTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006