Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9213 | 9213-30908 | Brazil | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K70R, M184V, T215F | D67S, K219E | K101E, Y181C, G190S | T39TA, T69N, K122E, T200A, R211A, K223KQ, L228H, V245T |
| >9213-30908| codons 38-247 CAEMEKEGKISKIGPENPYNTPVFAIKKKSSNRWRKLVDFRELNKRTQDFWEVQLGIPHP AGLEKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPDIVICQYVDDLYVSSDLEIGQHRAKIEELRQHLLAWGFFTP DEKHQQEPPFHWMGYELHPDKWTVQPITLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54T, V82A, L90M | L33F, G48I, F53L | L10V, T12TI, I15V, G16A, K20R, E34EQ, E35D, M36I, N37D, R41K, R57K, I62V, L63P, A71I, I72V, L89I, I93L |
| >9213-30908| codons 4-99 TLWQRPVVIIKVAGQLREALLDTGADDTVFQDIDLPGKWKPKMIIGIGGLTKVKQYDQVP IEICGHKIVGTVLVGPTPANIIGRNIMTQLGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |