Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-9071 | 9071-30901 | Brazil | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I47V, I54V, V82A, L90M | L33F, F53L, Q58E, N83D | L10V, G16A, K20R, E35D, M36I, N37D, R57K, D60E, Q61N, L63P, L89I |
| >9071-30901| codons 4-99 TLWQRPVVTIKIAGQLREALLDTGADDTVFEDIDLPGRWKPKIVGGIGGLVKVKEYENIP IEICGHKAIGTVLVGPTPADIIGRNIMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, L74I, M184V, T215Y | K103N | V118VI, K122E, D123E, T165I, Q174K, G196E |
| >9071-30901| codons 38-247 CTELEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKIVDFRELNKRTQDFWEVQLGIPHP AGLKKNKSVTVLDVGDAYFSIPLDEEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQSSMIKILEPFRKKNPDIVIYQYVDDLYVGSDLEIEQHRTKIEELRQHLLRWGFYTP DKKHQKEPPFLWMGYELHPDKWTVQPIVLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |