Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-7157 | 7157-30604 | Spain | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I15V, N37C, I62V, L63C, V77I |
| >7157-30604| codons 1-99 PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEEMCLPGRWKPKMIGGIGGFIKVRQYD QVCIEICGHKAIGTVLIGPTPVNIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, L210W, T215Y | E44ED, V118VI, D123DE, T200A, E203K, H208Y, R211K, K223E, L228R, K249Q, S251ST, A288S, V292I, E297K, S322T, I329L, A360V, A376T |
| >7157-30604| codons 1-399 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTELEKDGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL DKEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYMDDLYVGSDLEIGQHRAKIKELRQYLWKWGFYTPDKKHQEEPPFRWMGYELHPDKWT VQPIVLPEQDTWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGTKSLTEIIPLTKEAE LELAENREILKEPVHGVYYDPTKDLIAELQKQGQGQWTYQIYQEPFKNLKTGKYARMRGV HTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWE |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |