<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
48-7133 7133-30722 Spain 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, L74V, L210W, T215Y K219N K101E, K103HN, Y181C, G190A   E28K, K32E, V35I, T39A, K43Q, E44D, V118I, K122P, D123E, I135T, D177E, Q207DE, H208Y, R211K, K238S, A272P, K277R, V292I, I293IV, E297K, M357V, V365VI, K395R, E399D  
>7133-30722| codons 1-399
PISPIETVPVKLKPGMDGPKVKQWPLTKEKIEALIEICAELEQDGKISKIGPENPYNTPV
FAIKKKNSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLEKNKSVTVLDVGDAYFSIPL
DPEFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPEIVI
CQYMDDLYVASDLEIGQHRTKIEELREYLWKWGFYTPDNKHQKEPPFLWMGYELHPDSWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTEIVPLTKEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARVRGA
HTNDIKQLTEAVQKIATESIVIWGKTPKFKLPIQRETWD

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I54V, V82A, L90M K43KT L10I, K14KR, I15V, D60DE, I62IV, L63P, A71V  
>7133-30722| codons 1-99
PQITLWQRPIVTIRVGGQLKEALLDTGADDTVLEEMNLPGRWTPKMIGGIGGFVKVRQYE
QVPIEICGHKVIGTVLVGPTPANIIGRNLMTQIGCTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006