<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
48-7110 7110-30930 Spain 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, T69D, K70KR, L74I, V75T, M184V, T215F K219Q K101P, K103S   K20R, E28K, V35I, V118I, K122E, I135T, E169D, D177E, I178M, G196E, H208HY, F214L, A272P, P294A, Q334L, M357T, G359S, A371V, A376T, T386A  
>7110-30930| codons 1-399
PISPIETVPVKLKPGMDGPRVKQWPLTKEKIKALIEICTEMEKEGKISKIGPENPYNTPV
FAIKKKNSDRWRKITDFRELNKRTQDFWEVQLGIPHPAGLPKSKSVTVLDVGDAYFSIPL
DEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILDPFRKQNPEMVI
YQYVDDLYVGSDLEIEQHRTKIEELRQYLLRWGLFTPDQKHQKEPPFLWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTEVIALTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGLGQWTYQIYQEPFKNLKTGKYARTRSA
HTNDVKQLTEVVQKITTESIVIWGKAPKFKLPIQKETWE

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I47V, I54M, V82A, L90M F53FL L10V, L19I, K20R, E34Q, N37T, R41K, L63P, A71V, V77I, I93L  
>7110-30930| codons 1-99
PQITLWQRPVVTIKIGGQIREALLDTGADDTVLQEMTLPGKWKPKIVGGIGGLMKVRQYD
QIPIEICGHKVIGTVLIGPTPANIIGRNLMTQLGCTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006