<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
48-7106 7106-30910 Spain 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, M184V, L210W, T215Y V75M, N348I K103N   V35I, K43E, E44D, R83K, V90I, K102R, V118I, K122E, S162N, I178M, G196E, R211K, L228R, V245M, A272P, L283I, I293V, P294T, A355G, R356K, G359S, K366R, A371V, K385R, K390R  
>7106-30910| codons 1-400
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALIEICTELEEDGKISKIGPENPYNTPV
FAIKKKDSTKWRKLMDFRELNKKTQDFWEIQLGIPHPAGLKRNKSVTVLDVGDAYFSIPL
DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQNSMTKILEPFRKQNPDMVI
YQYVDDLYVGSDLEIEQHRTKIEELRQHLWKWGFYTPDKKHQKEPPFRWMGYELHPDKWT
VQPIMLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLIRGTKALTEVVTLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKILKTGKYGKMRSA
HTNDVRQLTEVVQKIATESIVIWGRTPKFRLPIQKETWEA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
V32I, M46I, I54V, I84V, L90M L10F, V11I, G73S, L89LV I15V, K20I, M36I, R41K, K55R, L63P, E65D, A71V  
>7106-30910| codons 1-99
PQITLWQRPFITIKVGGQLIEALLDTGADDTILEEINLPGKWKPKIIGGIGGFVRVRQYD
QIPIDICGHKVISTVLVGPTPVNVIGRNVMTQIGCTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006