<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
48-7102 7102-30728 Spain 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46MI, I47A, I84V   I13V, K20KT, L33V, N37C, R57K, L63P, I64V  
>7102-30728| codons 1-99
PQITLWQRPLVTVKIGGQLTEALLDTGADDTVVEEMCLPGRWKPKIAGGIGGFIKVKQYD
QIPVEICGHKAIGTVLVGPTPVNVIGRNLLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K65R, K70R, Q151M V75I, F77L, F116Y K103N   T27S, K49R, I50V, S68G, R83K, K122E, S163T, T165I, E169D, I195L, T200A, Q207E, R211K, F214FL, A272P, I293V, D324E, A355AT, T369A, A376T  
>7102-30728| codons 1-399
PISPIETVPVKLKPGMDGPKVKQWPLSEEKIKALVEICTEMEKEGKISRVGPENPYNTPV
FAIKRKDGTRWRKLIDLRELNKKTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYYSVPL
DEDFRKYTAFTIPSINNETPGIRYQYNVLPMGWKGSPAIFQSTMIKILDPFRKQNPDIVI
YQYMDDLYVGSDLELGQHRAKIEELREHLLKWGLTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTEVVPLTEEAE
LELAENREILKEPVHGVYYDPSKELIAEIQKQGQGQWTYQIYQEPFKNLKTGKYTRMRGA
HTNDVKQLAEAVQKITTESIVIWGKTPKFKLPIQKETWE

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006