Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-7102 | 7102-30728 | Spain | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46MI, I47A, I84V | I13V, K20KT, L33V, N37C, R57K, L63P, I64V |
| >7102-30728| codons 1-99 PQITLWQRPLVTVKIGGQLTEALLDTGADDTVVEEMCLPGRWKPKIAGGIGGFIKVKQYD QIPVEICGHKAIGTVLVGPTPVNVIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K65R, K70R, Q151M | V75I, F77L, F116Y | K103N | T27S, K49R, I50V, S68G, R83K, K122E, S163T, T165I, E169D, I195L, T200A, Q207E, R211K, F214FL, A272P, I293V, D324E, A355AT, T369A, A376T |
| >7102-30728| codons 1-399 PISPIETVPVKLKPGMDGPKVKQWPLSEEKIKALVEICTEMEKEGKISRVGPENPYNTPV FAIKRKDGTRWRKLIDLRELNKKTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYYSVPL DEDFRKYTAFTIPSINNETPGIRYQYNVLPMGWKGSPAIFQSTMIKILDPFRKQNPDIVI YQYMDDLYVGSDLELGQHRAKIEELREHLLKWGLTTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTEVVPLTEEAE LELAENREILKEPVHGVYYDPSKELIAEIQKQGQGQWTYQIYQEPFKNLKTGKYTRMRGA HTNDVKQLAEAVQKITTESIVIWGKTPKFKLPIQKETWE |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |