Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-7097 | 7097-30714 | Spain | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, M184V, T215F | K219E, N348I | Y188L | V35I, K122E, Q174K, N175Y, T200A, R211RK, L228H, E297K, K311R, I329L, Q334E, P345Q, M357T, A360T, A376T, S379C, V381VI, K390R |
| >7097-30714| codons 1-399 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALIEICTEMEKEGKISKIGPENPYNTPV FAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKKYPDIVI YQYVDDLLVGSDLEIGQHRAKIEELRQHLLKWGFFTPDEKHQKEPPFHWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGTKALTEVIPLTKEAE LELAENREILREPVHGVYYDPSKDLIAELQKQGEGQWTYQIYQEQFKILKTGKYARTRGT HTNDVKQLTEAVQKITTECIIIWGKTPKFRLPIQKETWE |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V32I, M46I, I47V, I54V, V82A | L10I, K14R, G16GE, K20R, E35D, M36I, L63P, A71V, I93L |
| >7097-30714| codons 1-99 PQITLWQRPIVTIRIEGQLREALLDTGADDTILEDINLPGRWKPKIVGGIGGFVKVRQYD QIPIEICGHKVIGTVLVGPTPANIIGRNLLTQLGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |