Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-7095 | 7095-30930 | Spain | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54V, I84V | L24I, L33F, T74P | L10I, T12P, K20T, E35D, M36I, N37Q, R57K, L63P, A71V, V77I, I93L |
| >7095-30930| codons 1-99 PQITLWQRPIVPIKIGGQLTEALIDTGADDTVFEDIQLPGRWKPKIIGGIGGFVKVKQYD QIPIEICGHKVIGPVLIGPTPVNVIGRNLLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, L74V, L210W, T215Y | Y181C | V108I | E6D, K43E, A98S, V118I, T200I, I202T, E203EAD, R211K, H221Y, L228R, E297KR, E312EG, V317G, I329V, G335C, T369A, A371V, A376AT, K390R |
| >7095-30930| codons 1-399 PISPIDTVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTELEEEGKISKIGPENPYNTPV FAIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPSGLKKKKSVTILDVGDAYFSIPL DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI CQYMDDLYVGSDLEIGQHRIKTDELRQHLWKWGFYTPDKKYQKEPPFRWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGTKALTEVIPLTREAE LELAENREILKGPVHGGYYDPSKDLIAEVQKQGQCQWTYQIYQEPFKNLKTGKYARMRGA HTNDVKQLAEVVQKITTESIVIWGKTPKFRLPIQKETWE |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |