Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-7093 | 7093-30929 | Spain | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K65R, Q151M | V75I, F77L, F116Y, K219Q | K101E, Y181C, G190A | K20R, S68G, T69I, V118I, K122E, Q174R, T200A, E204A, F214L, L228R, T286A, E297K, D324E, I329L, G335D, M357T, G359S, T369TA, V381I, K385R |
| >7093-30929| codons 1-399 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKRKDGIKWRKLIDLRELNKRTQDFWEVQLGIPHPAGLEKKKSVTVLDVGDAYYSIPL DEDFRKYTAFTIPSINNETPGIRYQYNVLPMGWKGSPAIFQSSMTKILEPFRKRNPDIVI CQYMDDLYVASDLEIGQHRAKIEALRQHLLRWGLTTPDQKHQKEPPFRWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTEVIPLTKEAE LELAENREILKEPVHGVYYDPSKELIAELQKQGQDQWTYQIYQEPFKNLKTGKYARTRSA HTNDVKQLAEAVQKIATESIIIWGRTPKFKLPIQKETWE |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54V, V82A, L90M | G73S | L10I, I15V, K20MV, L24LF, E35DN, M36I, N37D, D60E, I62V, L63P, A71V, I72L |
| >7093-30929| codons 1-99 PQITLWQRPIVTIKVGGQLVEALFDTGADDTVLENIDLPGRWKPKIIGGIGGFVKVRQYE QVPIEICGHKVLSTVLVGPTPANIIGRNLMTQIGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |