Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 48-7051 | 7051-30505 | Spain | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, T215TFIS | K219Q, N348I | K103N | K20R, K49R, K64NY, A98S, D123E, I178L, I195L, T200A, Q207HN, R211K, V245M, A272P, E297K, A327V, R358K, E370EA, A376S, T386I, K390R, A400T |
| >7051-30505| codons 1-400 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALVEICTEMEKEGKISRIGPENPYNTPV FAIYKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPSGLKKNKSVTVLDVGDAYFSVPL DKEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDLVI YQYMDDLYVGSDLELGQHRAKIEELRNHLLKWGFSTPDQKHQKEPPFLWMGYELHPDKWT VQPIMLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTEVIPLTKEAE LELAENREILKEPVHGVYYDPSKDLIVEIQKQGQGQWTYQIYQEPFKILKTGKYARMKGA HTNDVKQLTAAVQKISTESIVIWGKIPKFRLPIQKETWET |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| D30N | N88D | E35D, M36V, N37D, I62V, L63P, I64L, I72V, I93L |
| >7051-30505| codons 1-99 PQITLWQRPLVTIKIGGQLKEALLDTGADNTVLEDVDLPGRWKPKMIGGIGGFIKVRQYD QVPLEICGHKAVGTVLVGPTPVNIIGRDLLTQLGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |