<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
48-7024 7024-30915 Spain 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, K70R, V75M, T215Y K219Q, N348I K103KNRS, Y181C   K11KE, V35M, T39TA, V60I, D123E, I135T, D177E, I178M, G196E, H208Y, R211K, H221Y, L228H, A272P, K277R, T286A, I293V, M357T, A360T, T386I, K390KR  
>7024-30915| codons 1-398
PISPIETVPVELKPGMDGPKVKQWPLTEEKIKALMEICAELEKEGKISKIGPENPYNTPI
FAIKKKNSTRWRKLMDFRELNKRTQDFWEVQLGIPHPAGLKKSKSVTVLDVGDAYFSVPL
DKEFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPEMVI
CQYMDDLYVGSDLEIEQHRTKIEELRQYLLKWGFYTPDQKYQKEPPFHWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTEVVPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKILKTGKYARTRGT
HTNDVKQLTEAVQKIATESIVIWGKIPKFRLPIQKETW

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54V, V82T, I84V L24I, L33F L10I, R41K, F53FY, K55R, L63P, A71V, T91S  
>7024-30915| codons 1-99
PQITLWQRPIVTIKIGGQLKEALIDTGADDTVFEEMNLPGKWKPKIIGGIGGYVRVRQYD
QIPIEICGHKVIGTVLVGPTPTNVIGRNLLSQIGCTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006