Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
Treatment History
| Order | Regimen | Weeks |
| 1 | NFV | 28 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, N88S | Q58E | I13V, K14R, I15V, K20I, N37S, R41K |
| >503-152W28| codons 1-99 PQITLWQRPLVTVRVGGQLIEALLDTGADDTVLEEMSLPGKWKPKIIGGIGGFIKVREYD QILIEICGHKAIGTVLVGPTPVNIIGRSLLTQIGCTLNF |
References
| Author | Title | Citation |
| Patick, AK | Genotypic and phenotypic characterization of human immunodeficiency virus type 1 variants isolated from patients treated with the protease inhibitor nelfinavir. | AAC, 1998 |
| Wu, TD | Mutation patterns and structural correlates in human immunodeficiency virus type 1 protease following different protease inhibitor treatments. | J Virol, 2003 |
| Rhee, SY | HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. | J Infect Dis, 2005 |