<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
48-6209 6209-30715 Italy 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
G48V, I54CST, V82A, I84V   L10I, I13V, I15V, Q18H, K20I, E35D, M36I, N37D, Q61QH, A71I, P79S, Q92K  
>6209-30715| codons 1-99
PQITLWQRPIVTVKVGGHLIEALLDTGADDTVLEDIDLPGRWKPKMIVGIGGFTKVRQYD
HILIEICGHKIIGTVLVGSTPANVIGRNLLTKIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, M184V, T215Y       E28A, V35L, T39A, K43E, E44D, V118I, D123E, T200I, L210S, R211RK, D218E, V245Q, D250E, A272P, A288S, L289I, I293V, E297K, L301I, V317A, I329L, M357A, V365I  
>6209-30715| codons 1-399
PISPIETVPVKLKPGMDGPKVKQWPLTAEKIKALLEICAELEEDGKISKIGPENPYNTPV
FAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL
DKEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI
YQYVDDLYVGSDLEIGQHRIKIEELRQHLSKWGFYTPEKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKSITEVVPLTKEAE
IELAENREILKEPVHGAYYDPSKDLIAELQKQGQGQWTYQIYQEPFKNLKTGKYARARGA
HTNDIKQLTEAVQKIATESIVIWGKTPKFKLPIQKETWE

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006